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[Amend] No ____ no gain 

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[Amend] No ____ no gain

Answer

PAIN


Definition

Punishment suffered or denounced; suffering or evil inflicted as a punishment for crime, or connected with the commission of a crime; penalty.
Any uneasy sensation in animal bodies, from slight uneasiness to extreme distress or torture, proceeding from a derangement of functions, disease, or injury by violence; bodily distress; bodily suffering; an ache; a smart.
Specifically, the throes or travail of childbirth.
Uneasiness of mind; mental distress; disquietude; anxiety; grief; solicitude; anguish.
See Pains, labor, effort.
To inflict suffering upon as a penalty; to punish.
To put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture; as, his dinner or his wound pained him; his stomach pained him.
To render uneasy in mind; to disquiet; to distress; to grieve; as a child's faults pain his parents.